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Gene Control Part 2 (Prokaryotes): The Operon

Gene Control in Prokaryotes. The Operon Model.

User Comments

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I have a question about lac operon, I know that this happens only in prokaryotes but considering that the bacterias in the digestive tract do part of the breaking down for us, here is my chain of thoughts: E.Choli produces lactase if: -lactose is present and -if glucose level are low I have always drinked a lot of milk ( a lot!) but lately I have started being intolerant (big digestion problems, diarrhea etc :s) and this strangely coincides with a great increase in my glucose consumption (I found a candy wharehouse and buy a lot (a lot, a lot and a lot) of candies. Can the fact that I eat so much glucose inhibit my system's ability to digest lactose??
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A few errors in the video. It is allolactose (an isomer of lactose) not lactose that binds to the repressor protein in the lac operon. Also RNA polymerase is still able to perform transcription without CAP/cAMP complex just at a much lower rate. The only thing the CAP/cAMP complex does is increase the affinity of RNA polymerase to the promoter region therefore increase the chance RNA polymerase will bind and in turn increase the speed of lac operon transcription.
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Thanks for the video a lot but my teacher has mentioned that the level of tryptophan is also important for the transcription. He said if there is high level of tryptophan, the sides make some hairpin loop and there is poly u tail. He told us that means something like transcription terminal signal and it stops it. I am so sorry, I am not good enough to explain it :( I just was going to say that can you add it too, because I can't understand it 
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You sir, give some of the best verbal and visual descriptions I've ever heard/seen. I'm taking a genetics class at a university, and I have learned more from an hour watching your videos, than I have in my last 5 genetics classes. It has to take FOREVER to put those videos together! You seem very dedicated to your work, and you're very good at teaching. Seriously awesome work! Thank you!
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My teacher said there were two other possibilities of regulation in prokaryote cells. Something about decomposition of the RNAm before it reaches translation, as well as post-translation regulation where there is a decomposition of the polypeptide before it becomes a functional protein. Was this simply not included in the video or is my teacher crazy? :p
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Until two days ago I couldn't tell the difference between the DNA and a Gene. In just two days I was able to really comprehend not only which is which, but to also have a very good understanding of how the function. And all that, thanks to your very elaborate, pleasant to watch, and clear to understand videos Craig. Thank you!!!
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When the gene is open for transcription and the RNA can go on and read it, how is the overall quantity of the resulting protein controlled? Is it the case that the RNA keeps going back over and reading the gene over and over until the gene is eventually disabled and it can't be read? Really informative video thanks.
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Your teacher is correct. Those things can happen, but usually they are taught with Eukaryotic gene control. In this video I just focused on the operon. Check out my video on Eukryotic gene control for more info.
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A significant point - Archaea generally do not have genes in operons. Archaeal gene expression is much closer to that of Eukaryotes (although it varies by which groups of Archaea you consider).
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Thank you for the video, this helps a lot. One thing I could use some help with, how does this play into inducible versus repressible, and positive versus negative control?
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As I walked out of lecture today, I was utterly confused about the gene control. After watching your video, I have a much clearer idea. Thank you so much!
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you kept calling it RNA and mRNA that was binding to the DNA but it was really RNA Polymerase, a protein that produces RNA. very big difference
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Great explanation, thanks! I have never really understood lac operon after many biology courses.
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This is wonderful, thank you, you've wonderful, keep on making these videos pleaseeeeeee!!!!!
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You saved my time,and I only have few hours till the exam. Now I can go watch TV .Thank you!
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these videos have helped me so much! thank you so much for posting them!
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Thanks so much for job well done. i really love you calm and soft voice.
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best video i found on youtube for this thank u i greatly appreciate it
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Love your calm voice. Very understandable and easy to follow up with!
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By far the best explanation on operons I have seen. Good show!
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Great to watch just before an exam :) thanks to put this on.
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This helped a lot. My bio teacher doesn't teach us shit
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Wow...what a explanation.. Absolutely love it....
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Your videos are amazing! Thank you soooo much!
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Thanks a mill!!! you just helped me aced my exam
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Thanks. This video was easy to understand.
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Good job! u made it simple than i thought
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Helped do much !! thank- you so much !!!

Anime Sucks and Here's Why [dalek14mc commentary]

Misleading title is misleading. No I don't hate anime, watch more than 3 seconds of the video and you would probably realize this. --- Original video: ...

User Comments

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I hate anime because the writing is shit. I love the gore and rape though. The sex too *nod*. I hate the writing because of lines like "You!!!!!"
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Um...okay. Huh. Well then. You're a freak.
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The people who are going to argue with this video saying that something like "ANIME 4 LIFE!!" Or something they are more than likely a 12 year old girl or something.
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Well, I can tell you one thing. I'm not a twelve year old...nor am I female. So...have you ever seen Elfen Lied?
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Here's the anime Community 99% Ignorant,Immature,ruthless,obsessed,Psychotic teenagers 9001 yes... IT'S OVER 9000!!! They say that all Cartoons are utterly shit then they worship the devil because They worship anime and Boku no Pico is the devil's work at least cartoons don't aim for pedophiles.
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+Otrera Citlali Weeaboo:Someone who is EXTREMELY obsessed with Japan culture who bashes other media especially Western Animation.
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+Shinigami No that's called obsessed. Retard.
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More like 86% I like anime but I'm not the 99%
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+Retard Scanner that's called a weeaboo
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+Shinigami Some of them aren't even trolls some of them are ignorant enough to be serious.
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+Retard Scanner well, that's called a troll.
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+Shinigami yes but they still worship Anime as a god and thd reason why I call them ignorant,Immature,obsessed, ruthless and psychotic that They have the balls to threaten kids with killing them because of the cartoons they like!!!
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You mean weeaboos. And 99.99 percent of the community hates boku no pico.
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Finally I get a chance to reply. I think this guy disliked Elfen Lied a lot xD 10 - Big eyes is what makes anime unique and different. It adds emotions to a persons face. Most of the times its the eyes which speak louder than the words. If you observe carefully then the eyes in anime convey much more emotions than in cartoons. 9 - Stupid Titles? Not all anime have stupid titles and sometimes they do have a deep meaning. Nice point but not enough to prove that anime sucks. 8 - Idle faces...hmm...The voice acting in anime is brilliant and does not require 24/7 moving hands. The eyes first of all depict emotions like I said in point 10. Its one of the ways used to make anime beautiful. 7 - Overuse of demons...Lol a few anime have demons does not mean all of them do have. And by the way for those few anime who have demons are usually used to make the story sound more exciting and better. And check out once more only some anime have demons. And the violence is used to make the story more touching and add a realistic feel unlike cartoons. 6 - Violence is not meant to scare the audience always. It is used to make the story more touching and to add a realistic thrilling experience. What is more better? A person being stabbed with a sword and getting hurt without bleeding or a person stabbed with a sword whose pain could be felt through the hearts of the audience due to some of the realistic bloodshed? 5 - Anime mainly doesnt focus on that. We have a seperate set called Hentai for that stuff. And it is not always something on which viewers are expected to focus mainly on. Its just there to add a bit of funny element in a different manner as far as its not Hentai 4 - what the hell was that supposed to mean? Trying to fill stuff to make a top 10? 3 - Well this is one of the qualities of anime. Overly Dramatic death scenes? They leave the viewer depressed and the pain of the death of an anime character could be felt in the viewers hearts. This ability of the anime is actually awesome and i appreciate it. The Death scenes actually make give it the feel of a death scene. Anime brings feelings to life in such ways. 2 - Bizzare characters? Lol dont get me wrong but cartoons as the name says have a lot more bizarre characters. There are a few wierd anime characters but there is nothing wrong with that. Have you watched how many bizarre characters cartoons have? And well it depends on the genre of the anime. If the genre is about something like aliens it will sure have bizarre characters. 1 - Death Of Children? So children dont die in real life? Dont get me wrong but this time I have to say that if your a faint of heart then u should not watch such anime. Anime adds real life emotions to computerized moving figures. And it depends again on the story of the anime. If Death of children do happen in real life then there is nothing wrong with it happening in anime. I HAVE SPOKEN UP
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This is just a clickbait and he said that this is top ten Anime clichés.
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1 question: Why does Lucy aka Nyu appear every so often in this video? ^_^
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+Eugenefindit Oh. I see what you did there. They are to indicate your turn to speak, eh. ^_^
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